Lysergic acid diethylamide (also known as Lysergide, LSD-25, LSD, L, Lucy, and Acid). Is a classical psychedelic substance of the lysergamide class. It is perhaps the most researched and culturally influential psychedelic substance, as well as the prototypal lysergamide. Buy LSD online California Buy DMT in Los Angeles San Diego San Jose Order MDMA online Sacramento San Francisco Oakland Buy Ketamine in Long Beach
The psychoactive effects of LSD were first discovered in 1943 by Albert Hofmann at Sandoz Laboratories (Switzerland). During this era, it provoked considerable. Interest from the intellectual establishment and was even the subject of a clandestine investigation by the U.S. Central Intelligence Agency (CIA) for potential applications in “mind control”.
Recreational LSD use became a central, highly-visible aspect of the 1960s youth counterculture movement. Eventually paving the way for international prohibition in 1971. The lifetime prevalence of LSD use among American adults is 6-8%.
Following decades of institutional suppression, scientific research involving LSD has recently undergone a massive revival.
Subjective effects include visual geometry / hallucinatory states, time distortion. Enhanced introspection, conceptual thinking, increased music appreciation, euphoria, and ego loss.
However, adverse psychological reactions such as severe anxiety, paranoia, delusions. And psychosis are always possible, particularly for those predisposed to mental disorders (see this section).
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The name LSD comes from its early research code name LSD-25. An abbreviation for the German spelling “Lysergsäure-diethylamid” followed by a sequential number.
LSD has numerous street names including: acid, lucy, L, cid or sid. Also called blotter or tabs, a reference to their standard form of distribution.
LSD, or d-lysergic acid diethylamide, belongs to a class of synthetic organic compounds called lysergamides (a subclass of ergolines).
These include: 1B-LSD, 1P-LSD, 1V-LSD, ALD-52, AL-LAD, ETH-LAD, PRO-LAD, LSM-775, LSZ, and MiPLA.
The chemical structure consists of a bicyclic hexahydroindole ring fused to a bicyclic quinoline group (lysergic acid). Buy LSD online California Buy DMT in Los Angeles San Diego San Jose Order MDMA online Sacramento San Francisco Oakland Buy Ketamine in Long Beach
It is a chiral compound with two stereocenters at R5 and R8. The other three stereoisomers do not have psychoactive properties.
The pure form occurs as colorless, odorless, prismatic crystals. It is sensitive to oxygen, ultraviolet light, and chlorine (especially in solution).
According to various studies, LSD acts as a partial agonist at most serotonin receptor subtypes. Including the 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C and 5-HT6 receptors, with high affinities.
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Further information about how altered serotonin signaling may lead to LSD’s. Signature cascade of visual and cognitive effects is available here.
Recent research has also found that LSD activates different intracellular signaling. Cascades than endogenous serotonin even when bound to the same receptor sites. Because intracellular signaling cascades influence gene expression, LSD-induced signaling events within cells may inappropriately. Alter gene expression, which in turn may lead to changes in neuronal state and subsequently cognition.
These findings help explain why the behavioral effects can resemble paranoid schizophrenia in humans.
Additionally, studies have shown that LSD possesses binding efficacy at all dopamine and all norepinephrine receptors. Most serotonergic psychedelics are not significantly dopaminergic, so LSD is unique in this respect. Buy LSD online California Buy DMT in Los Angeles San Diego San Jose Order MDMA online Sacramento San Francisco Oakland Buy Ketamine in Long Beach